Irish data on the safety and efficacy of vedolizumab in the treatment of inflammatory bowel disease

Introduction: Vedolizumab (VDZ) is a monoclonal antibody designed to inhibit α4β7 integrin and result in gut-selective anti-inflammatory activity. Real-world data are important in providing information to clinicians on the effectiveness and safety of this agent.Methods: A retrospective, multi-centre study was conducted across 9 Irish academic centres. Adult (≥18 years) patients receiving VDZ for active IBD (ulcerative colitis [UC] or Crohn’s...