Immunomodulatory and Anti-Inflammatory Strategies to Reduce Comorbidity Risk in People with HIV

In this review, we will discuss treatment interventions targeting drivers of immune activation and chronic inflammation in PWH. Potential treatment strategies to prevent the progression of comorbidities in PWH have been identified. These studies include, among others, the use of statins to modulate lipid alterations and subsequent innate immune receptor activation, probiotics to restore healthy gut microbiota and reduce microbial translocation,...