MicroRNA-17-5p regulates EMT by targeting vimentin in colorectal cancer
Abstract
Background Epithelial–mesenchymal transition (EMT) is the most common cause of death in colorectal cancer (CRC). In this study, we investigated the functional roles of miRNA-17-5p in EMT of CRC cells. Methods In order to determine if miRNA-17-5p regulated EMT, the precursors and inhibitors of miR-17-5p were transduced into four CRC cells. To evaluate the regulatory mechanism, we performed argonaute 2 (Ago2) immunoprecipitation (IP) and...
Paper Details
Title
MicroRNA-17-5p regulates EMT by targeting vimentin in colorectal cancer
Published Date
Jun 17, 2020
Journal
Volume
123
Issue
7
Pages
1123 - 1130
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