MicroRNA-17-5p regulates EMT by targeting vimentin in colorectal cancer

Volume: 123, Issue: 7, Pages: 1123 - 1130
Published: Jun 17, 2020
Abstract
Background Epithelial–mesenchymal transition (EMT) is the most common cause of death in colorectal cancer (CRC). In this study, we investigated the functional roles of miRNA-17-5p in EMT of CRC cells. Methods In order to determine if miRNA-17-5p regulated EMT, the precursors and inhibitors of miR-17-5p were transduced into four CRC cells. To evaluate the regulatory mechanism, we performed argonaute 2 (Ago2) immunoprecipitation (IP) and...
Paper Details
Title
MicroRNA-17-5p regulates EMT by targeting vimentin in colorectal cancer
Published Date
Jun 17, 2020
Volume
123
Issue
7
Pages
1123 - 1130
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