Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk
Abstract
In breast cancer, high levels of homeobox protein Hox-B13 (HOXB13) have been associated with disease progression of ER-positive breast cancer patients and resistance to tamoxifen treatment. Since HOXB13 p.G84E is a prostate cancer risk allele, we evaluated the association between HOXB13 germline mutations and breast cancer risk in a previous study consisting of 3,270 familial non- BRCA1/2 breast cancer cases and 2,327 controls from the...
Paper Details
Title
Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk
Published Date
Jun 16, 2020
Journal
Volume
10
Issue
1
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