A network-based computational framework to predict and differentiate functions for gene isoforms using exon-level expression data
Abstract
Alternative splicing makes significant contributions to functional diversity of transcripts and proteins. Many alternatively spliced gene isoforms have been shown to perform specific biological functions under different contexts. In addition to gene-level expression, the advances of high-throughput sequencing offer a chance to estimate isoform-specific exon expression with a high resolution, which is informative for studying splice variants with...
Paper Details
Title
A network-based computational framework to predict and differentiate functions for gene isoforms using exon-level expression data
Published Date
May 1, 2021
Journal
Volume
189
Pages
54 - 64
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