Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities
Abstract
Periventricular white matter hyperintensities (WMH; PVWMH) and deep WMH (DWMH) are regional classifications of WMH and reflect proposed differences in cause. In the first study, to date, we undertook genome-wide association analyses of DWMH and PVWMH to show that these phenotypes have different genetic underpinnings.Participants were aged 45 years and older, free of stroke and dementia. We conducted genome-wide association analyses of PVWMH and...
Paper Details
Title
Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities
Published Date
Jul 1, 2020
Journal
Volume
51
Issue
7
Pages
2111 - 2121
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