Abstract A44: Functional models of chromosome arm-level aneuploidies in cancer
Abstract
Aneuploidy, whole-chromosome or chromosome arm copy number imbalance, is a near-universal characteristic of human cancers. We previously applied methods that define chromosome arm-level aneuploidy and a global cancer aneuploidy score to 10,522 tumors of 33 types in The Cancer Genome Atlas (TCGA). Aneuploidy level was correlated with TP53 mutation, somatic mutation rate, and expression of proliferation genes. Overall aneuploidy was...
Paper Details
Title
Abstract A44: Functional models of chromosome arm-level aneuploidies in cancer
Published Date
Jun 1, 2020
Journal
Volume
80
Issue
11_Supplement
Pages
A44 - A44
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