Productive herpesvirus lytic replication in primary effusion lymphoma cells requires S-phase entry
Abstract
Gammaherpesviruses establish lifelong latent infection in B lymphocytes and are the causative agent of several B-cell malignancies and lymphoproliferative disorders. While a quiescent latent infection allows these pathogens to evade immune detection, initiation of an alternative lifecycle stage, known as lytic replication, is an essential step in the production and dissemination of infectious progeny. Although cessation of cellular proliferation...
Paper Details
Title
Productive herpesvirus lytic replication in primary effusion lymphoma cells requires S-phase entry
Published Date
Aug 1, 2020
Journal
Volume
101
Issue
8
Pages
873 - 883
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