Original paper
Developmental Programming: Sheep Granulosa and Theca Cell–Specific Transcriptional Regulation by Prenatal Testosterone
Abstract
Prenatal testosterone (T)-treated sheep, similar to polycystic ovarian syndrome women, manifest reduced cyclicity, functional hyperandrogenism, and polycystic ovary (PCO) morphology. The PCO morphology results from increased follicular recruitment and persistence of antral follicles, a consequence of reduced follicular growth and atresia, and is driven by cell-specific gene expression changes that are poorly understood. Therefore, using RNA...
Paper Details
Title
Developmental Programming: Sheep Granulosa and Theca Cell–Specific Transcriptional Regulation by Prenatal Testosterone
Published Date
Jun 9, 2020
Volume
161
Issue
8
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