Fenofibrate ameliorates testicular damage in rats with streptozotocin-induced type 1 diabetes: role of HO-1 and p38 MAPK

Volume: 72, Issue: 6, Pages: 1645 - 1656
Published: Jun 9, 2020
Abstract
Since diabetes mellitus type-1 (DM-1) induces testicular oxidative and inflammatory damage with finally an ultimate male infertility, and as fenofibrate (FEN) plays an important antioxidant and anti-inflammatory role, the aim of the present study was to investigate the effects of FEN on diabetes-induced reproductive damage and clarifying the underlying related mechanisms. DM-1 was induced in male Wistar rats by a single intraperitoneal injection...
Paper Details
Title
Fenofibrate ameliorates testicular damage in rats with streptozotocin-induced type 1 diabetes: role of HO-1 and p38 MAPK
Published Date
Jun 9, 2020
Volume
72
Issue
6
Pages
1645 - 1656
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