Epigenetic prediction of major depressive disorder

Volume: 26, Issue: 9, Pages: 5112 - 5123
Published: Sep 1, 2021
Abstract
Variation in DNA methylation (DNAm) is associated with lifestyle factors such as smoking and body mass index (BMI) but there has been little research exploring its ability to identify individuals with major depressive disorder (MDD). Using penalised regression on genome-wide CpG methylation, we tested whether DNAm risk scores (MRS), trained on 1223 MDD cases and 1824 controls, could discriminate between cases (n = 363) and controls (n = 1417) in...
Paper Details
Title
Epigenetic prediction of major depressive disorder
Published Date
Sep 1, 2021
Volume
26
Issue
9
Pages
5112 - 5123
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