Incerta-thalamic Circuit Controls Nocifensive Behavior via Cannabinoid Type 1 Receptors

Neuron16.20
Volume: 107, Issue: 3, Pages: 538 - 551.e7
Published: Aug 1, 2020
Abstract
•ZIv parvalbumin-positive neurons participate in nocifensive behaviors•ZIv-Po pathway bi-directionally regulates nocifensive behaviors•CB1Rs express at the circuit terminals and control nocifensive behaviors•ZIv-Po circuit and cannabinoids regulate pathological pain Pain is a source of substantial discomfort. Abnormal activity in both the zona incerta (ZI) and posterior complex of the thalamus (Po) are implicated in neuropathic pain, but their...
Paper Details
Title
Incerta-thalamic Circuit Controls Nocifensive Behavior via Cannabinoid Type 1 Receptors
Published Date
Aug 1, 2020
Journal
Volume
107
Issue
3
Pages
538 - 551.e7
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