Salty Taste: From Transduction to Transmitter Release, Hold the Calcium

Neuron16.20
Volume: 106, Issue: 5, Pages: 709 - 711
Published: Jun 1, 2020
Abstract
Detection of NaCl by the gustatory system is fundamental for salt intake and tissue homeostasis. Yet, signal transduction mechanisms for salty taste have remained obscure. In this issue of Neuron, Nomura et al. (2020) report that the epithelial sodium channel ENaC, which serves as the salty receptor, is co-expressed with the voltage-activated ATP release channel CALHM1/3 in a subset of taste cells and that these cells mediate amiloride-sensitive...
Paper Details
Title
Salty Taste: From Transduction to Transmitter Release, Hold the Calcium
Published Date
Jun 1, 2020
Journal
Volume
106
Issue
5
Pages
709 - 711
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