Evaluation of the Autonomic Nervous System in a Canine Model of Chronic Embolic Pulmonary Hypertension

Sildenafil improves autonomic dysfunction caused by pulmonary hypertension (PH) in humans, but its effect is unknown in dogs with PH. This prospective study aimed to evaluate the autonomic nervous system function of a canine model of chronic embolic PH (CEPH) and the autonomic nervous system function of a canine model of CEPH in which sildenafil was administered. This study used five clinically healthy female beagle dogs. Evaluation parameters...