Interactions of Hematopoietic Stem Cells with Bone Marrow Niche
Abstract
Hematopoietic stem cells (HSCs) are ultimately responsible for the lifelong renewal of all blood cell lineages. In the bone marrow (BM), HSCs reside in specialized microenvironments referred to as the "niche." HSC niche consists of complex components including heterogeneous cell populations, growth factors, and extracellular matrix molecules. The crosstalk between HSCs and their niche is essential to regulate the survival, self-renewal,...
Paper Details
Title
Interactions of Hematopoietic Stem Cells with Bone Marrow Niche
Published Date
Jan 1, 2020
Journal
Pages
21 - 34
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