BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control
Abstract
Obesity is a leading cause of preventable death worldwide. Despite this, current strategies for the treatment of obesity remain ineffective at achieving long-term weight control. This is due, in part, to difficulties in identifying tolerable and efficacious small molecules or biologics capable of regulating systemic nutrient homeostasis. Here, we demonstrate that BAM15, a mitochondrially targeted small molecule protonophore, stimulates energy...
Paper Details
Title
BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control
Published Date
Jun 10, 2020
Journal
Volume
12
Issue
7
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