Integrative tumor and immune cell multi-omic analyses to predict melanoma response to immune checkpoint blockade.
Volume: 38, Issue: 15_suppl, Pages: 10009 - 10009
Published: May 20, 2020
Abstract
10009 Background: The complex crosstalk between tumor and immune cells during immune checkpoint blockade mandates the development of integrated models to interpret the antitumor immune response and predict clinical outcome. Methods: We performed comprehensive genomic, transcriptomic and T cell repertoire analyses on tumor biopsies from 64 patients with advanced melanoma receiving nivolumab +/- ipilimumab on CheckMate-038 (NCT01621490). Tumor...
Paper Details
Title
Integrative tumor and immune cell multi-omic analyses to predict melanoma response to immune checkpoint blockade.
Published Date
May 20, 2020
Journal
Volume
38
Issue
15_suppl
Pages
10009 - 10009
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