Top down thinking: how uncrossmatched RBCs confounded ABO typing

Obtaining a valid type and screen is an essential step in ensuring recipient safety. When a patient receives uncrossmatched group O red blood cells (RBCs) because of an urgent need for transfusion, it is important that the sample for the type and screen is drawn early in the resuscitation to prevent these cells from interfering with the determination the recipient's native ABO type in the forward typing. A recent study demonstrated that the ABO...