Secreted BMP antagonists and their role in cancer and bone metastases

Bone4.10
Volume: 137, Pages: 115455 - 115455
Published: Aug 1, 2020
Abstract
Bone morphogenetic proteins (BMPs) are multifunctional secreted cytokines that act in a highly context-dependent manner. BMP action extends beyond the induction of cartilage and bone formation, to encompass pivotal roles in controlling tissue and organ homeostasis during development and adulthood. BMPs signal via plasma membrane type I and type II serine/threonine kinase receptors and intracellular SMAD transcriptional effectors. Exquisite...
Paper Details
Title
Secreted BMP antagonists and their role in cancer and bone metastases
Published Date
Aug 1, 2020
Journal
Volume
137
Pages
115455 - 115455
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