Effects of adiposity on the human plasma proteome: Observational and Mendelian randomization estimates

Published: Jun 3, 2020
Abstract
null Background null Variation in adiposity is associated with cardiometabolic disease outcomes, but the mechanisms leading from this exposure to disease are unclear. This study aimed to estimate effects of adiposity, proxied by body mass index (BMI), on an extensive set of circulating proteins using both observational and genetically informed analyses. null Methods and findings null We used proteomic data from up to 2,737 healthy participants...
Paper Details
Title
Effects of adiposity on the human plasma proteome: Observational and Mendelian randomization estimates
Published Date
Jun 3, 2020
Journal
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