A Simple and Scalable Strategy for Analysis of Endogenous Protein Dynamics
Abstract
The ability to analyze protein function in a native context is central to understanding cellular physiology. This study explores whether tagging endogenous proteins with a reporter is a scalable strategy for generating cell models that accurately quantitate protein dynamics. Specifically, it investigates whether CRISPR-mediated integration of the HiBiT luminescent peptide tag can easily be accomplished on a large-scale and whether integrated...
Paper Details
Title
A Simple and Scalable Strategy for Analysis of Endogenous Protein Dynamics
Published Date
Jun 2, 2020
Journal
Volume
10
Issue
1
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