MS-SMART study: systematic sampling bias concerns

We read the results of the MS-SMART trial reported by Jeremy Chataway and colleagues in The Lancet Neurology comparing the efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis. We noted that they did not find evidence of neuroprotective efficacy for the three therapeutics under investigation.1Chataway J De Angelis F Connick P et al.Efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis...