Interplay of curcumin and its liver metabolism on the level of Aβ in the brain of APPswe/PS1dE9 mice before AD onset

Volume: 72, Issue: 6, Pages: 1604 - 1613
Published: May 28, 2020
Abstract
An increasing number of studies have shown that Alzheimer’s disease (AD) is a systemic disease characterized by brain dysfunction. In this study, we aimed to investigate the effects of curcumin on the liver, an important metabolic organ, and on the brain in APPswe/PS1dE9 (APP/PS1) mice, and the interaction between these effects. Curcumin was administered to 5-month-old APP/PS1 transgenic mice for 7 consecutive days using the intragastric (ig)...
Paper Details
Title
Interplay of curcumin and its liver metabolism on the level of Aβ in the brain of APPswe/PS1dE9 mice before AD onset
Published Date
May 28, 2020
Volume
72
Issue
6
Pages
1604 - 1613
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