Systemic delivery of peptides by the oral route: Formulation and medicinal chemistry approaches
Abstract
In its 33 years, ADDR has published regularly on the po5tential of oral delivery of biologics especially peptides and proteins. In the intervening period, analysis of the preclinical and clinical trial failures of many purported platform technologies has led to reflection on the true status of the field and reigning in of expectations. Oral formulations of semaglutide, octreotide, and salmon calcitonin have completed Phase III trials, with oral...
Paper Details
Title
Systemic delivery of peptides by the oral route: Formulation and medicinal chemistry approaches
Published Date
Jan 1, 2020
Volume
157
Pages
2 - 36
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