Rapid generation of rotavirus single-gene reassortants by means of eleven plasmid-only based reverse genetics
Abstract
Reassortment is an important mechanism in the evolution of group A rotaviruses (RVAs), yielding viruses with novel genetic and phenotypic traits. The classical methods for generating RVA reassortants with the desired genetic combinations are laborious and time-consuming because of the screening and selection processes required to isolate a desired reassortant. Taking advantage of a recently developed RVA reverse genetics system based on just 11...
Paper Details
Title
Rapid generation of rotavirus single-gene reassortants by means of eleven plasmid-only based reverse genetics
Published Date
Jun 3, 2020
Journal
Volume
101
Issue
8
Pages
806 - 815
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