A multicenter phase 1 study of nivolumab for relapsed hematologic malignancies after allogeneic transplantation.
Abstract
Programmed cell death-1 (PD-1)/programmed death ligand-1 blockade may potentially augment graft-vs-tumor effects following allogeneic hematopoietic cell transplantation (alloHCT), but retrospective studies of anti-PD-1 therapy reported substantial toxicity from graft-versus-host-disease (GVHD). Here, we report the results of a prospective clinical trial of PD-1 blockade for relapsed hematologic malignancies (HMs) after alloHCT (NCT01822509). The...
Paper Details
Title
A multicenter phase 1 study of nivolumab for relapsed hematologic malignancies after allogeneic transplantation.
Published Date
Jun 11, 2020
Journal
Volume
135
Issue
24
Pages
2182 - 2191
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Notes
History