Mathematical model of the ventricular action potential and effects of isoproterenol-induced cardiac hypertrophy in rats
Abstract
Mathematical action potential (AP) modeling is a well-established but still-developing area of research to better understand physiological and pathological processes. In particular, changes in AP mechanisms in the isoproterenol (ISO) -induced hypertrophic heart model are incompletely understood. Here we present a mathematical model of the rat AP based on recordings from rat ventricular myocytes. In our model, for the first time, all channel...
Paper Details
Title
Mathematical model of the ventricular action potential and effects of isoproterenol-induced cardiac hypertrophy in rats
Published Date
May 27, 2020
Journal
Volume
49
Issue
5
Pages
323 - 342
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