Dehydration as a possible tool to slow down peritoneal metastases by changing the intraperitoneal environment.

e16037 Background: Due to limited efficiency of current intravenous and intraperitoneal chemotherapeutic approaches, treating advanced peritoneal metastases (PM) remains an ongoing oncologic challenge. As the peritoneum is an optimal biological compartment for metastatic growth, stopping progressive tumor extension at more advanced stages is currently unachievable. With this study, we aim to investigate whether changing the intraperitoneal...