Dietary Fatty Acid Composition Is Associated with FTO Gene Expression in Human Visceral and Subcutaneous Adipose Tissues

The fat mass and obesity-associated gene (FTO) is a functional candidate gene for type 2 diabetes mellitus (T2DM) and metabolic syndrome, based on evidence from genome-wide association studies (GWAS) that linked it to obesity and metabolic disorders. The FTO gene regulates energy expenditure and intake. We aimed to determine how fatty acid species measured in plasma and dietary intake associate with FTO gene expression in subcutaneous and...