Urinary markers of nucleic acid oxidation increase with age, obesity and insulin resistance in Danish children and adolescents
Abstract
Oxidative stress may play an important role in childhood obesity and increased cardiometabolic risk. 8-oxo-7,8-dihydroguanosine (8-oxoGuo) from oxidation of RNA and 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) from oxidation of DNA are excreted into urine and function as biomarkers for oxidative stress reflecting the modification rate of nucleic acids by oxidation. This study investigates the associations between urinary markers of nucleic acid...
Paper Details
Title
Urinary markers of nucleic acid oxidation increase with age, obesity and insulin resistance in Danish children and adolescents
Published Date
Aug 1, 2020
Volume
155
Pages
81 - 86
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