Activation of DNA damage repair factors in HPV positive oropharyngeal cancers
Abstract
The mechanisms regulating viral pathogenesis of human papillomavirus (HPV) associated oropharyngeal squamous cell cancers (OPSCC) are not well understood. In the cervix, activation of DNA damage repair pathways is critical for viral replication but little is known about their role in OPSCC. APOBEC factors have been shown to be increased in OPSCC but the significance of this is unclear. We therefore examined activation of DNA damage and APOBEC...
Paper Details
Title
Activation of DNA damage repair factors in HPV positive oropharyngeal cancers
Published Date
Aug 1, 2020
Journal
Volume
547
Pages
27 - 34
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