Estimating the Impact of Verification Bias on Celiac Disease Testing

The goal of this study was to estimate the impact of verification bias on the diagnostic accuracy of immunoglobulin A tissue transglutaminase (IgA tTG) in detecting celiac disease as reported by an authoritative meta-analysis, the 2016 Comparative Effectiveness Review (CER).Verification bias is introduced to diagnostic accuracy studies when screening test results impact the decision to verify disease status.We adjusted the sensitivity and...