The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges
Abstract
Ubiquitin Proteasome System (UPS) is an adaptable and finely tuned system that sustains proteostasis network under a large variety of physiopathological conditions. Its dysregulation is often associated with the onset and progression of human diseases; hence, UPS modulation has emerged as a promising new avenue for the development of treatments of several relevant pathologies, such as cancer and neurodegeneration. The clinical interest in...
Paper Details
Title
The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges
Published Date
Sep 1, 2020
Journal
Volume
213
Pages
107579 - 107579
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