Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473
Abstract
Human thermogenic adipose tissue mitigates metabolic disease, thus raising much interest in understanding its development and function. Here, we show that human thermogenic adipocytes specifically express a primate-specific long noncoding RNA (lncRNA), LINC00473, which is highly correlated with UCP1 expression and is decreased in obesity and type-2 diabetes. LINC00473 is detected in progenitor cells, and increases following differentiation and...
Paper Details
Title
Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473
Published Date
May 21, 2020
Journal
Volume
2
Issue
5
Pages
397 - 412
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