Stapled Peptide Inhibitors of Autophagy Adapter LC3B

A growing body of evidence suggests that autophagy inhibition enhances the effectiveness of chemotherapy, especially in difficult‐to‐treat cancers. Existing autophagy inhibitors are primarily lysosomotropic agents. More specific autophagy inhibitors are highly sought‐after. The microtubule‐associated protein 1A/1B light chain 3B protein, LC3B, is an adapter protein that mediates key protein‐protein interactions at several points in autophagy...