Do AKT1, COMT and FAAH influence reports of acute cannabis intoxication experiences in patients with first episode psychosis, controls and young adult cannabis users?

Chandni Hindocha; Diego Quattrone; Tom P. Freeman; Robin M. Murray; Valeria Mondelli; Gerome Breen; Charles Curtis; Celia J. A. Morgan; H. Valerie Curran; Marta Di Forti

doi:https://doi.org/10.1038/s41398-020-0823-9

doi.org/10.1038/s41398-020-0823-9

Do AKT1, COMT and FAAH influence reports of acute cannabis intoxication experiences in patients with first episode psychosis, controls and young adult cannabis users?

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..., Marta Di Forti

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Translational Psychiatry6.80

Volume: 10, Issue: 1

Published: May 12, 2020

Abstract

Epidemiological and biological evidence support the association between heavy cannabis use and psychosis. However, it is unclear which cannabis users are susceptible to its psychotogenic effect. Therefore, understanding genetic factors contributing to this relationship might prove an important strategy to identify the mechanisms underlying cannabis-associated psychotic experiences. We aimed to determine how variation in AKT1, COMT and FAAH...