Directed differentiation of regulatory T cells from naive T cells and prevention of their inflammation-mediated instability using small molecules
Volume: 201, Issue: 2, Pages: 205 - 221
Published: Jun 8, 2020
Abstract
Summary Regulatory T (Treg) cell therapy is a promising approach for immune tolerance induction in autoimmunity conditions and cell/organ transplantations. Insufficient isolation yields and impurity during downstream processes and Treg instability after adoptive transfer in inflammatory conditions are major limitations to Treg therapy, and indicate the importance of seeking a valid, reliable method for de-novo generation of Tregs. In this...
Paper Details
Title
Directed differentiation of regulatory T cells from naive T cells and prevention of their inflammation-mediated instability using small molecules
Published Date
Jun 8, 2020
Volume
201
Issue
2
Pages
205 - 221
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