High bone density and radiographic osteoarthritis: questions answered and unanswered

Osteoarthritis (OA) has long been known to be associated with high bone mineral density (BMD). Epidemiological studies are consistent in finding that older women and men who have higher systemic BMD (i.e., BMD measured at appendicular and axial sites distal from joints) have an increased risk for the subsequent onset, or incidence, of knee radiographic OA (ROA)1Nevitt M.C. Zhang Y. Javaid M.K. Neogi T. Curtis J.R. Niu J. et al.High systemic bone...