Unintended on-target chromosomal instability following CRISPR/Cas9 single gene targeting
Abstract
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) seminal studies in mammalian cells1Jinek M. East A. Cheng A. Lin S. Ma E. Doudna J. RNA-programmed genome editing in human cells.eLife. 2013; 2013: 1-9Google Scholar, 2Cong L. Ran F.A. Cox D. et al.Multiplex genome engineering using CRISPR/Cas systems.Science. 2013; 339: 819-823Crossref PubMed Scopus (8697) Google Scholar, 3Mali P. Yang L....
Paper Details
Title
Unintended on-target chromosomal instability following CRISPR/Cas9 single gene targeting
Published Date
Sep 1, 2020
Journal
Volume
31
Issue
9
Pages
1270 - 1273
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Notes
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