Integrated urine proteomics and renal single-cell genomics identify an IFN-γ response gradient in lupus nephritis
Abstract
Lupus nephritis, one of the most serious manifestations of systemic lupus erythematosus (SLE), has a heterogeneous clinical and pathological presentation. For example, proliferative nephritis identifies a more aggressive disease class that requires immunosuppression. However, the current classification system relies on the static appearance of histopathological morphology, which does not capture differences in the inflammatory response....
Paper Details
Title
Integrated urine proteomics and renal single-cell genomics identify an IFN-γ response gradient in lupus nephritis
Published Date
Jun 18, 2020
Journal
Volume
5
Issue
12
Pages
137788
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