The Null Hypothesis of IFN-γ and Monocyte Function in Leishmaniasis

Volume: 27, Issue: 5, Pages: 683 - 684
Published: May 1, 2020
Abstract
The phagosomal pathogen Leishmania appears unaffected by deliberate changes in the early Th1/Th2 balance. In this issue, Carneiro et al. explain these paradoxical results by showing that manipulations affecting IFN-γ-mediated phagocyte activation are counteracted by effects on IFN-γ-dependent recruitment of CCR2+ monocytes permissive to parasite growth. The phagosomal pathogen Leishmania appears unaffected by deliberate changes in the early...
Paper Details
Title
The Null Hypothesis of IFN-γ and Monocyte Function in Leishmaniasis
Published Date
May 1, 2020
Volume
27
Issue
5
Pages
683 - 684
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