Developmental exposure to 17α‐hydroxyprogesterone caproate impairs adult delayed reinforcement and reversal learning in male and female rats

Women with a history of unexplained miscarriage are frequently prescribed the synthetic progestin, 17α‐hydroxyprogesterone caproate (17‐OHPC) during the middle trimester of pregnancy. However, little is known about the long‐term behavioural effects of 17‐OHPC. Work in rodents suggests that the developing brain is sensitive to progestins. Neonatal 17‐OHPC impairs adult performance in set‐shifting and delay discounting. The present study tested...