Germ cell loss in Klinefelter syndrome: When and why?

Volume: 184, Issue: 2, Pages: 356 - 370
Published: May 15, 2020
Abstract
Klinefelter syndrome (KS) is a quite common disorder with an incidence of 1–2 in 1,000 new-born males. Most patients are diagnosed in the light of a clinical checkup when consulting a fertility clinic with an unfulfilled child wish. Infertility in KS patients is caused by a massive germ cell loss, leading to azoospermia in more than 90% of the adult patients. Most seminiferous tubules in the adult KS testis are degenerated or hyalinized and...
Paper Details
Title
Germ cell loss in Klinefelter syndrome: When and why?
Published Date
May 15, 2020
Volume
184
Issue
2
Pages
356 - 370
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