Original paper
Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis model
Abstract
Epoxyeicosatrienoic acids (EET) and related epoxy fatty acids (EpFA) are endogenous anti-inflammatory compounds, which are converted by the soluble epoxide hydrolase (sEH) to dihydroxylethersatrienoic acids (DHETs) with lessened biological effects. Inhibition of sEH is used as a strategy to increase EET levels leading to lower inflammation. Rheumatoid arthritis is a chronic autoimmune disease that leads to destruction of joint tissues. This...
Paper Details
Title
Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis model
Published Date
May 13, 2020
Journal
Volume
34
Issue
7
Pages
9074 - 9086
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Notes
History