The Challenges of Vaccine Development against a New Virus during a Pandemic

The rapid emergence of a highly pathogenic, readily transmissible coronavirus has resulted in a global pandemic, affecting millions and destabilizing economies. This catastrophe triggered a clarion call for the immediate deployment of a protective vaccine. We describe the unique challenges of developing a vaccine against SARS-CoV-2 in a pandemic setting. The rapid emergence of a highly pathogenic, readily transmissible coronavirus has resulted...