The effect of disaggregated nano-hydroxyapatite on oral biofilm in vitro

Agglomeration is a common problem facing the preparation and application of nanomaterials, and whether nano-hydroxyapatite (nano HA) can modulate oral microecology left to be unclear. In this study, nano HA was disaggregated by sodium hexametaphosphate (SHMP) and ultrasonic cavitation to observe whether agglomeration would affect its effect on oral bacterial biofilm. Dynamic light scattering (DLS) and scanning electronic microscope (SEM) were...