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Is Recovery of Somatosensory Impairment Conditional for Upper-Limb Motor Recovery Early After Stroke?:

Published on May 11, 2020in Neurorehabilitation and Neural Repair3.757
· DOI :10.1177/1545968320907075
Sarah B. Zandvliet1
Estimated H-index: 1
(VU: VU University Amsterdam),
G. Kwakkel71
Estimated H-index: 71
(NU: Northwestern University)
+ 2 AuthorsCarel G. M. Meskers5
Estimated H-index: 5
(NU: Northwestern University)
Abstract
Background. Spontaneous recovery early after stroke is most evident during a time-sensitive window of heightened neuroplasticity, known as spontaneous neurobiological recovery. It is unknown whether poststroke upper-limb motor and somatosensory impairment both reflect spontaneous neurobiological recovery or if somatosensory impairment and/or recovery influences motor recovery. Methods. Motor (Fugl-Meyer upper-extremity [FM-UE]) and somatosensory impairments (Erasmus modification of the Nottingham Sensory Assessment [EmNSA-UE]) were measured in 215 patients within 3 weeks and at 5, 12, and 26 weeks after a first-ever ischemic stroke. The longitudinal association between FM-UE and EmNSA-UE was examined in patients with motor and somatosensory impairments (FM-UE /=18 at 26 weeks (n = 55) showed a significant positive association between motor and somatosensory impairments, irrespective of progress of time. Conclusions. Progress of time, as a reflection of spontaneous neurobiological recovery, is an important factor that drives recovery of upper-limb motor as well as somatosensory impairments in the first 12 weeks poststroke. Severe somatosensory impairment at baseline does not directly compromise motor recovery. The study rather suggests that spontaneous recovery of somatosensory impairment is a prerequisite for full motor recovery of the upper paretic limb.
  • References (65)
  • Citations (1)
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References65
Newest
#1G. KwakkelH-Index: 71
#2E.E.H. van Wegen (VU: VU University Amsterdam)H-Index: 14
Last. Frederike van WijckH-Index: 18
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The second Stroke Recovery and Rehabilitation Roundtable “metrics” task force developed consensus around the recognized need to add kinematic and kinetic movement quantification to its core recomme...
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#1Robinson Kundert (ETH Zurich)H-Index: 1
#2Jeffrey D. Goldsmith (Columbia University)H-Index: 36
Last. Andreas Luft (UZH: University of Zurich)H-Index: 23
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In 2008, it was proposed that the magnitude of recovery from nonsevere upper limb motor impairment over the first 3 to 6 months after stroke, measured with the Fugl-Meyer Assessment (FMA), is appro...
5 CitationsSource
#1Juan Pablo SaaH-Index: 1
#2Tamara TseH-Index: 8
Last. Leeanne M. CareyH-Index: 33
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Background Cognitive impairment affects up to 80 percent of the stroke population, however, both the available evidence about post-stroke cognition and the measures used to evaluate it longitudinally have not been well described. The aims of this systematic scoping review were: to identify and characterize studies evaluating cognition longitudinally after stroke; to summarize the cognitive instruments used and the domains they target; and to organize cognitive domains assessed using the Internat...
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#1Jos W. R. TwiskH-Index: 94
#2Wieke de Vente (UvA: University of Amsterdam)H-Index: 16
Abstract Objectives The interpretation of a regression coefficient obtained from a longitudinal data analysis is a combination of a within-subject part and a between-subject part. The hybrid model is used to disentangle the two components. The purpose of this article was to illustrate and discuss the use of the hybrid model in epidemiologic studies. Study Design and Setting In the hybrid model the between-subject part of the relationship is obtained using the individual mean value over time, whe...
Source
#1Megan L. Turville (La Trobe University)H-Index: 4
#2Liana S. Cahill (ACU: Australian Catholic University)H-Index: 3
Last. Leeanne M. Carey (La Trobe University)H-Index: 33
view all 5 authors...
Objective:The aim of this study was to evaluate if somatosensory retraining programmes assist people to improve somatosensory discrimination skills and arm functioning after stroke.Data sources:Nine databases were systematically searched: Medline, Cumulative Index to Nursing and Allied Health Literature, PsychInfo, Embase, Amed, Web of Science, Physiotherapy Evidence Database, OT seeker, and Cochrane Library.Review methods:Studies were included for review if they involved (1) adult participants ...
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#1Megan L. Turville (La Trobe University)H-Index: 4
#2Thomas A. Matyas (La Trobe University)H-Index: 38
Last. Leeanne M. Carey (La Trobe University)H-Index: 33
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BACKGROUND: Somatosensory loss occurs often following stroke. A proportional recovery model is proposed for spontaneous motor recovery, with implication for treatment planning. It is currently unknown if initial severity of sensory impairment influences stroke survivors' response to treatment to improve sensation. OBJECTIVE: To examine if initial (pre-treatment) severity of upper limb somatosensory impairment is related to sensation outcomes following treatment. METHODS: Regression analysis was ...
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#1Thomas M. H. Hope (UCL: University College London)H-Index: 14
#2Karl J. Friston (UCL: University College London)H-Index: 192
Last. Howard Bowman (UKC: University of Kent)H-Index: 28
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The proportional recovery rule asserts that most stroke survivors recover a fixed proportion of lost function. To the extent that this is true, recovery from stroke can be predicted accurately from baseline measures of acute post-stroke impairment alone. Reports that baseline scores explain more than 80%, and sometimes more than 90%, of the variance in the patients’ recoveries, are rapidly accumulating. Here, we show that these headline effect sizes are likely inflated. The key effects in this l...
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#2Miriana Jlenia Quattromani (Lund University)H-Index: 5
Last. Adam Q. Bauer (WashU: Washington University in St. Louis)H-Index: 19
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Stroke causes direct structural damage to local brain networks and indirect functional damage to distant brain regions. Neuroplasticity after stroke involves molecular changes within perilesional tissue that can be influenced by regions functionally connected to the site of injury. Spontaneous functional recovery can be enhanced by rehabilitative strategies, which provides experience-driven cell signaling in the brain that enhances plasticity. Functional neuroimaging in humans and rodents has sh...
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#1Caroline Winters (VUmc: VU University Medical Center)H-Index: 4
#2G. KwakkelH-Index: 71
Last. Carel G. M. Meskers (NU: Northwestern University)H-Index: 5
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BACKGROUND: Stroke rehabilitation aims to reduce impairments and promote activity and participation among patients. A major challenge for stroke rehabilitation research is to develop interventions that can reduce patients' neurological impairments. Until now, there has been no breakthrough in this research field. To move stroke rehabilitation forward, we need more knowledge about underlying mechanisms that drive spontaneous (i.e., reactive) neurobiological recovery after stroke and factors that ...
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#1Leonardo Boccuni (Katholieke Universiteit Leuven)H-Index: 2
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#2Jeffrey D. Goldsmith (Columbia University)H-Index: 36
Last. Andreas Luft (UZH: University of Zurich)H-Index: 23
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In 2008, it was proposed that the magnitude of recovery from nonsevere upper limb motor impairment over the first 3 to 6 months after stroke, measured with the Fugl-Meyer Assessment (FMA), is appro...
5 CitationsSource