Recent advances in understanding the role of hypoxia-inducible factor 1α in renal fibrosis
Volume: 52, Issue: 7, Pages: 1287 - 1295
Published: May 6, 2020
Abstract
Renal fibrosis is the most common pathological manifestation of chronic kidney disease (CKD), and with numerous influencing factors, its pathogenesis is complex. Epithelial-mesenchymal transition (EMT) is known to promote the progression of renal fibrosis via alterations in the secreted proteome. Moreover, blocking or even reversing EMT can effectively reduce the degree of fibrosis. As such, targeting the key molecules responsible for promoting...
Paper Details
Title
Recent advances in understanding the role of hypoxia-inducible factor 1α in renal fibrosis
Published Date
May 6, 2020
Volume
52
Issue
7
Pages
1287 - 1295
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