Targeting glycosylated antigens on cancer cells using siglec‐7/9‐based CAR T‐cells
Abstract
Chimeric antigen receptor (CAR) T-cells treatment demonstrate the increasing and powerful potential of immunotherapeutic strategies, as seen mainly for hematological malignancies. Still, efficient CAR-T cell approaches for the treatment of a broader spectrum of tumors are needed. It has been shown that cancer cells can implement strategies to evade immune response that include the expression of inhibitory ligands, such as hypersialylated...
Paper Details
Title
Targeting glycosylated antigens on cancer cells using siglec‐7/9‐based CAR T‐cells
Published Date
May 11, 2020
Journal
Volume
59
Issue
7
Pages
713 - 723
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History