Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity

Volume: 11, Issue: 1
Published: May 11, 2020
Abstract
Death due to sepsis remains a persistent threat to critically ill patients confined to the intensive care unit and is characterized by colonization with multi-drug-resistant healthcare-associated pathogens. Here we report that sepsis in mice caused by a defined four-member pathogen community isolated from a patient with lethal sepsis is associated with the systemic suppression of key elements of the host transcriptome required for pathogen...
Paper Details
Title
Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity
Published Date
May 11, 2020
Volume
11
Issue
1
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